Allows you to store up a lot of tears in the air and release them all at once. Isaac will also be immune to other sources such as Mom's leg stomp, Satan's leg stomp. * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red, Item Pool: Boss Room, Challenge Room, Beggar, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly, Item Pool: Boss Room, Beggar, Challenge Room, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow, * boss room pool, boss room item, brown, leather, bag, sack. Cosmetic change only. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, The laser can apply status effects (e.g. Robo-Baby's lasers deal 3.5 damage per hit. * 20 20, 2020, item room, treasure room, item room pool, black glasses, spectacles. Damage dealt is equal to your tear damage * 2. UNLOCK: Unlock this item by beating the Chest with Azazel. Can be negated with Black Candle, Bad Gas - Isaac farts, poisoning enemies around him, Bombs are key - Switches number of bombs and keys, Explosive Diarrhea - Spawns five live troll bombs behind Isaac, one per second, Full Health - Restores all your empty red heart containers, Health Down - -1 HP. Despite the very small tears visually, Proptosis is always a damage up at any range for tears. Item Pool: Devil Room, Greed Mode Devil Room. The tears from each bomb deal a flat 25 damage and are affected by any tear modifiers Isaac has. UNLOCK: Unlock this item by killing Mom (Mom's Foot or Mom's Heart) using The Bible. If an enemy is killed while it is golden, it will drop between 1-4 coins. Will teleport you to out of the room if used in a Boss Room or Devil Room. * item room, treasure room, item room pool, white, grey, gray, bloody. * shop room pool, shop item pool, the lost item pool, white. Increases the time that status effects stay on enemies. This item works with items which can be purchased such as shop items, allowing you to spawn a free version if the effect triggers. Gives Isaac an eternal heart and the ability to fly. * shop room pool, shop item pool, stopwatch, blue, pocket, clock. *, mr me!, Mr Meeseeks, rick and morty, brown, chest, szechuan sauce, Grants a prism orbital with a large orbital radius, Isaac's tears that pass through the prism split into four multi-colored tears, Does not deal contact damage to enemies that it passes over, Added as part of the Afterbirth+ Booster Pack #3. Chests now have a 50/50 chance to either pay out with extra consumables or nothing/an enemy. * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, dead, black, grey, Tears up (not applied until the next time your tears stat is updated). Enjoy unrivalled analysis of England's Euro 2022 victory and more, with the Sports Newspaper of the Year. * devil pool, devil room pool, devil deal, grey, gray, bloody. If a parasitoid shot successfully hits an enemy, a blue friendly fly or spider is spawned. Grants a secondary chance of any non-specific heart drop turning into a soul heart. In addition to the familiars, any blue flies or spiders will be converted to 1 coin each. UNLOCK: Unlock this item by using 4 XIII - Death cards. If used on a trinket, another random trinket will spawn instead of a duplicate. Gives the player the Whore of Babylon effect for the current room, increasing damage and speed. Isaac's normal bombs become pink and causes them to drop random pickups when they explode (e.g. red, drip. UNLOCK: Unlock this trinket by beating Challenge #27 (Brains). Decreases range stat by -4.25 but increases your tear height by 1.5, increasing your actual tear range. * slot machine, arcade machine, money, bill, cash, green, * boss rush pool, boss rush room, item room, treasure room, item room pool, grey, gray, x10. When used, this rune deals 40 damage to all enemies in the room and consumes all pedestal items in the room, giving you a random stat increase for each item consumed. As you hold down the fire button, shots will float in the same place until you release the fire key again. A familiar that follows Isaac and leaves blood creep on the floor as it floats, hurting enemies that walk over it for 2 damage per tick. Bombs, keys, cards, runes and batteries have a 20% chance. UNLOCK: Unlock this item by beating Challenge #16 (Computer Savvy). It will not 'double' your familiars as the tagline suggests - if you have 2 of one kind, it will only give you an extra one. UNLOCK: Unlock this item by beating Boss Rush with Eve. While this trinket is held you have a significantly lower chance to find spacebar/active items. Spoon Bender, Telepathy for Dummies, I - The Magician). See the Broken Shovel / Mom's Shovel items for more information on how to unlock. Collecting a second Ball of Bandages in the run turns the orbital into a pink head that shoots tears that deal 7 damage each and have a chance to charm enemies. * tech 10, tech ten, donut laser rings, vr, headset, visor. * shop room pool, shop item pool, blue, grey, gray, smashed, clock. Can be used to generate infinite consumable combinations, gaining as many coins/keys/bombs as you need. - Speeds up all enemies for the rest of the room. Has no recharge time and can be used as often as you like. Unlocked from Challenge #24 - PAY TO PLAY, Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect), Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. Summons 3 blue friendly spiders and 3 blue flies. poop, pots, TNT, red poop, stone blocks etc.). UNLOCK: Unlock this trinket by beating Ultra Greed with Keeper. Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) and many others. Pre-Afterbirth this dealt 4 or 6 damage, instead of scaling with your tear damage. Spider Mod will also randomly drop battery consumables or blue spiders when a room is completed. Ghost Baby fires tears at a rate of 1 tear per second. Every 3 rooms Acid Baby will drop a random pill, Every time you use a pill, Acid Baby will poison all enemies in the room, dealing double your tear damage to each of them, A familiar fairy that will float around the room and highlight the location of any secret room doors, tinted rocks or trapdoors under rocks, Upon entering a new room, if there is an undiscovered secret room or tinted rock, it will move directly to the point of interest, otherwise it will just randomly fly around the room, For every empty red heart container, Isaac gains +0.2 Damage Up and his body increases in size. The shield will rotate based on the direction in which Isaac is firing tears. The spear cannot be thrown like Mom's Knife but deals damage while it is in contact with an enemy. The tear type changes every few seconds. *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health. The angel will attract bullets towards it and block them. Based on the Steam Workshop mod created by Merlo. Can be used to generate infinite batteries with the 48 hour energy pill. Cannot spawn a trapdoor directly infront of a secret room entrance. After taking damage, if you have half a red heart or less, The Polaroid will give you an invincibility shield for 5 seconds. Spoon Bender will give them a homing effect), Tears which fall naturally to the floor at max range do not generate sparks. The Wafer becomes most effective in the Womb and beyond where enemies all deal a whole heart of damage. Beating the Boss Rush while holding this item will drop the second half of the Broken Shovel, which combine to create Mom's Shovel, which is used to unlock The Forgotten character, Dropping the Broken Shovel will cause it to disappear if you leave the room, NOTE: This item will not drop unless you have beaten The Lamb at least once, Added as part of the Afterbirth+ Booster Pack #5 and used in the quest to unlock The Forgotten character, Drops after beating the Boss Rush while holding the other half of the Broken Shovel (see previous item for more details), Combines with the first Broken Shovel piece to create Mom's Shovel (see next item for more details), When used, spawns a trapdoor that leads to the next floor (has a 10% chance to be a crawl space instead), Unlocks The Forgotten character when used on a mound of dirt that appears in a room in The Dark Room floor. This is very similar to a Skatole for spiders instead of flies. Holes in the ground can be filled by crushing adjacent rocks, similar to how this can be done with bombs. Upon entering a new room that already has hearts on the ground, they will all be converted into Black Hearts. UNLOCK: Unlock this card by beating Challenge #1 (Pitch Black). *, red, grey, gray, brown, black, red, eyes. Will hurt Isaac if he is in the blast radius. Spawns some troll bombs at random locations in the current room. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar, Bomb Beggar. Damaged reduction is reduced from every source in the game except Devil Deals and health down pills. Everytime you fire a tear, there is a chance that you will also fire three more tears in all cardinal directions. Item Pool: None (Blood donation machine only). Upon use, takes away one full heart and deals 40 damage to the entire room. * item room, treasure room, item room pool, dungeon room, blood challenge room, arena pool, Based on the Steam Workshop mod created by Strawrat and Aczom. Increases your chances of getting a devil/angel room by +12.5% (Before Afterbirth DLC this was a guaranteed 100%). Each tear now has a small chance to be a fire instead, which deals 23 damage to enemies that come in contact with it. * item room, treasure room, item room pool, raccoon, green. Using bombs or your active item will remove the invicibility as well. * golden chest pool, gold chest pool, dead, cat, white, yellow. Holding Rib of Greed increase your chance to receive coin drops. cash money. * angel room pool, god room pool, angel room item, red, fire, flame, orange, cross. * item room, treasure room, item room pool, blue remote, robot. UNLOCK: Unlock this item by beating the Basement 40 times and defeating the Steven boss. * item room, treasure room, item room pool, the lost item pool, black, grey, gray, bat. This means any damage taken or consumables used in the current room will be reset back to the previous state. First half of the key required to enter the door to the Mega Satan boss. Boss rush door: Will open the Boss Rush door from either side, allowing you get into and escape the Boss Rush. trinket (e.g. UNLOCK: Unlock this item by beating Challenge #18 (The Host). * item room, treasure room, item room pool, large eye, cyclops, one eye, blue, white. * , the lost item pool, tong, red, bloody, lips. * tinted rock, marked rock, grey, gray, lump, white. Attack Fly, Dart Fly, Eternal Fly, and Ring Fly are transformed into a neutral black fly. Isaac's tears turn bright green and always apply a poison effect to enemies which deals a total of double your tear damage. There's Options, Double item room, Boss Rush) the Moving Box will pick only one of the items at random, Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by HurleyFarrill. Tears now have a chance to concuss enemies, causing them to walk around dazed and confused for a short period of time. Item Pool: Item Room, Secret Room, Key Beggar, *, grey, gray, black, face, stone, rock, baby. Possible mushrooms include: Mini Mush, Odd Mushroom (Thin), Odd Mushroom (Thick), The Compass. Item Pool: Item Room, Devil Room, Curse Room, Demon Beggar, * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool devil pool, devil room pool, devil deal, item room, treasure room, item room pool, gimp mask, the lost item pool, grey, gray, black. When used, turns Isaac invincible and gains +0.28 speed for a 5 seconds. This allows for a full 360 degree tear firing radius. * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, If you get close enough to an enemy that has a large hitbox, you can hit it with 2 of the laser beams, allowing you to deal a lot more damage. The chance to activate the invincibility effect is affected by your luck stat and at +38 Luck it will activate every time you get hit. * anti gravity, item room, treasure room, item room pool, anti gravity, atom, nucleus. Trisagion tears deal roughly 33% of your usual tear damage, however due to the size of the holy flash it is likely to hit enemies multiple times, Trisagion tears cause no knockback on enemies and simply travel through them (piercing tears), Added as part of the Afterbirth+ Booster Pack #4. Causes all item pedestals to be chosen from a random item pool instead of the pre-defined ones which normally exist. UNLOCK: Unlock this item by beating Boss Rush with Lilith. Gives you a familiar demon incubus that follows you and shoots tears exactly the same as Isaac's in terms of damage, stats and also effects. the lost item pool, brown, white, cross, * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, syringe, needle, injection, white. UNLOCK: Unlock this item by beating Greed Mode with ???. In general if a card has a number of things, that thing is doubled. Any further Ball of Bandages will repeat the cycle. Upon use, teleports you to one of the following rooms at random: Item room, Secret room, Super secret room, the I AM ERROR room or the Black Market (very low chance). While you're firing tears Hushy will stop moving, which allows you to keep it in one place. * , the lost item pool, playing, card, white, red. Items which increase your shot speed cause the tear to travel faster across the screen. * red chest pool, red chest item pool, shop room pool, shop item pool, blue box. Using this item gives you a higher chance of finding a horsemen boss at the end of the floor. Gives Isaac a slight glow when Curse of Darkness is active. While firing tears constantly for 7.5 seconds, you spawn a poop cloud, which deals periodic damage to any enemies which come near it. This item works for the Keeper, allowing him to exceed his usual 2 health containers. UNLOCK: Unlock this item by defeating Greedier Mode with Lilith. UNLOCK: Unlock this item by defeating Greedier Mode with Isaac. Every time you take damage, 10 high damage tears are fired in a circle around you (similar to the Tammy's Head effect). When used, the D7 will restart the current room and bring back all enemies once again, enabling you to farm rewards that spawn at the end after beating the room. Upon use, this item freezes all enemies in the room until you press the fire button again or 30 seconds passes (whichever happens first). Based on the Steam Workshop mod created by electoon and Erfly, *, dark side of the moon, rainbow, red, yellow, green, white, triangle, pink floyd, thought, Replaces Isaac's tears with eyeballs that can bounce off of each other, Issac's tears are no longer limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle, Added as part of the Afterbirth+ Booster Pack #3. Bomb damage = damage * 5 + 30 (Pre-afterbirth this was damage * 3). Each of the tears in the cluster deals double damage, When entering a room connected to a Secret Room or Super Secret Room, a howling sound will play, When entering a room with a crawl space trapdoor in it, a barking sound will play. UNLOCK: Unlock this trinket by donating 666 coins to the Greed Donation Machine. Using the box again will put the picked up items back on the floor again, allowing you to move things between rooms, Can move any of the following: Batteries, Items, Trinkets, Hearts, Keys, Bombs, Coins, Chests and more. In Afterbirth this item synergises with Brimstone and Tech, allowing them to do more damage the further away the enemy is. * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green. When Isaac takes damage, the bottle breaks and leaves a pool on the floor which deals 8 damage per tick to enemies which walk over it. Enemies have a chance to drop half a red heart when killed. When used, fires a 4 way brimstone laser in all cardinal directions, dealing a lot of damage to any enemies. Check waiting times and death rates at your local hospital, Join Camilla Tominey at our unmissable hustings event on 11 Aug in Cheltenham, Play our new PlusWord puzzle for free. Has a 22.22% chance to respawn with 3 Soul hearts as Blue Baby when you die. UNLOCK: Unlock this item by beating Challenge #15 (Slow Roll). Bombs no longer automatically explode and will only do so when you activate the remote detonator. UNLOCK: Unlock this item by beating Boss Rush with Cain. Dangerous to use in early floors, it could replace a basement enemy with something usually found in the Womb only. Temporarily makes Isaac huge, giving him +7 Damage Up and +30 Range Up for the rest of the current room, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Coper140. * item room, treasure room, item room pool, pink, body part. Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost'. The effect stacks if used multiple times. When used, copies the effect of the card or rune you are currently holding without consuming it. A familiar blue fly that will follow Isaac's movement pattern but delayed by 1 second. Gives you the Fruit Cake effect for the room when used, which will give a random tear effect with every tear fired. Gives you a Tonsil familiar, which follows Isaac and blocks enemy projectiles. Resurrection takes place before all other items which give you an extra life, * secret room pool, mario, green mushroom, extra life, spots, spotted. When it explodes, it deals 110 damage to everything in radius (Same damage as Mr Mega bombs). A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage. She can only spawn a maximum of up to 5 spiders at a time and will only do so while there are enemies in the room. Tears fired at the minimum possible charge do roughly 1/3 of your normal damage. * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, Teleports the player to the Boss room on the current floor. Robo-Baby's laser is spectral and piercing (It will pass through rocks and objects in the environment). For example, with Yum Heart you would heal 2 full red hearts instead of 1. Every time you get hit, you have a chance to activate the D6, D20, D8 or D12 effect. Every time you kill an enemy a fly will be added to the Jar, allowing you to stack up to 20. * item room, treasure room, item room pool, yellow, chet lemon. Unlocked from Challenge #25 - Have a Heart, Feels like I'm walking on sunshine! UNLOCK: Unlock this item by defeating The Lamb in the Dark Room floor as The Forgotten. Synergizes very well with a lot of items. When used will teleport you to another random room that has not been explored yet. Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc. Increases the size of your player sprite, but doesn't increase the hitbox. UNLOCK: Unlock this item by beating Greed Mode with Eden. The amount of tears fired in the charge depends on how long you charge for. This effect stacks with multiple shades, scaling the contact damage each time. A familiar that follows Isaac and blocks tears. Counts as 1 of 3 spider items needed towards the Spider Baby transformation. This will affect all hearts including red, soul and black, reducing all of them down to half of one heart. UNLOCK: Unlock this trinket by defeating Isaac in the Cathedral as Apollyon. Items which increase your tears stat will cause the tear to deal damage at a faster rate. Allows you to reflect projectiles away from Isaac (Afterbirth only feature). Using Moving Box with Car Battery will trigger 2 interactions at the same time: First it will drop all items currently inside the box and secondly will then pick up the current room's contents. 4 cubes of meat cause the meat boy familiar to grow in size and do 5.5 damage per tick instead. shop room pool, shop item pool,red, robot, head, cube. UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times. * angel room pool, god room pool, angel room item, blue, silver, metal. If a trinket has been smelted, it won't appear a second time unless the entire trinket pool is exhausted or you restart the run (e.g. When you die with this item, you respawn in the same room with 1 heart and the Anemic item. Tap the drop button to cycle between each one. "Poke that power outlet! Upon use, does 10 damage to all enemies in the room and gives them a slowing effect for 4 seconds. +0.2 Damage Up for each 'evil' item you have. UNLOCK: Unlock this item by defeating Greedier Mode with Eden. UNLOCK: Unlock this item by sleeping in 10 different beds. UNLOCK: Unlock this item by defeating Delirium in The Void floor with Isaac. Gives Isaac a familiar Gurdy that will charge around the room dealing contact damage to enemies. UNLOCK: Unlock this item by beating Mom's Heart 8 times. * item room, treasure room, item room pool, fetus in a jar, bug, white, hat, pink. Can only happen once per room. If an active item is consumed, its effect will be added to Void's effect when used, allowing you to consume multiple items and combine their effects. After a few seconds, the crosshair will disappear, and the Ghost will do certain things based on what you targeted: Items, pickups, trinkets: Brings them to Isaac. * item room, treasure room, item room pool, grey, gray, worm. chalice, indiana jones, * angel room pool, god room pool, angel room item, bird, white. Each booger persists until the enemy is dead or 60 seconds has passed. Will also synergize with some other items, such as Mom's Eye, Brimstone, Dr. Fetus, Tech X or Loki's Horns, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Kieran and Stewartisme, Allows you to rapidly place bombs on the ground, Added as part of the Afterbirth+ Booster Pack #1. UNLOCK: Keeper starts with this trinket after beating Satan with Keeper. * item room, treasure room, item room pool, grey, gray, magnet. Tap the drop button to cycle between each one. * item room, treasure room, item room pool, black, grey, gray. The laser deals damage equal to double your tear damage. * item room, treasure room, item room pool, cheetos, cheese, grey, gray, orange, jar. (Does not roll your devil deal items). Stat Down becomes Stat Up, 'Bad Trip' turns into 'Balls of Steel' and 'Amnesia' turns into 'I can see forever'. Gives Isaac an orbital knife that blocks shots and deals 15 damage per tick on contact with enemies. Soul hearts and black hearts cannot be stored. Instantly kills the Mom's Foot, Mom's Heart and It Lives boss fights. Be warned though, Mom's leg can also stomp and hurt Isaac too! Item Pool: Item Room, Library, Secret Room, * library pool, library room, book room pool, secret room pool, item room, treasure room, * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac. Item Pool: Item Room, Library, Devil Room, * library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red 7 book, grey, gray, black.